Личная информация
- Страна местожительства: Jordan
Информация
Curriculum Vitae
Accreditation and quality assurance center
The University of Jordan
1
Personal Information
Name Heba M. Kalbouneh
Place and date of birth Wadi Seer 28/12/1982
Faculty Medicine
Department Anatomy and histology
Qualifications
University of donor Date
rank
Qualification Specialization
Anatomy and cell University of Heidelberg 2013
biology
PhD
Anatomy, Histology & University of Jordan 2008
Embryology
MSc
Doctor of dental University of Jordan 2005
surgery
DDS
Specialization and domain of interest
Specialization Anatomy and cell biology
Domain of interest Neurological diseases, Radiographic and clinical anatomy
Specialization and domain of interest
Title and abstract of the doctoral thesis (within 150 words)
The functional consequences of gephyrin phosphorylation on inhibitory synapses.
CDK5 has been implicated in neural functions including growth, neuronal migration,
synaptic transmission and plasticity of excitatory chemical synapses. Here we report robust
effects of CDK5 on phosphorylation of the postsynaptic scaffold protein gephyrin and
clustering of inhibitory GABAA receptors in hippocampal neurons. shRNA-mediated
knockdown of CDK5 and pharmacological inhibition of cyclin-dependent kinases reduced
phosphorylated gephyrin clusters and postsynaptic c2-containing GABAA receptors.
Phosphorylation of S270 is antagonized by PP1/PP2a phosphatase and site directed
mutagenesis and in vitro phosphorylation experiments indicate that S270 is a putative
CDK5 phosphorylation site of gephyrin. Our data suggest that CDK5 plays an essential role
for the stability of gephyrin-dependent GABAA receptor clusters in hippocampal neurons.
Accreditation and quality assurance center Curriculum Vitae The University of Jordan
2
Career Experience
Job Title Place of work Date
Department of Anatomy, School of Sep 2013- Current
Medicine, University of Jordan
Assistant professor
Department of Anatomy, Faculty of Sep 2010-Sep 2013
Medicine, University of Heidelberg
PhD student
Department of Anatomy, School of Oct 2008- Sep 2010
Medicine, university of Jordan
Lecturer
Department of Anatomy, School of Sep 2006- Oct 2008
Medicine, University of Jordan
Teaching and
research assistant
Dentist Private dental clinic Feb 2006- Sep 2006
Dentist-internship Ministry of health July 2005-Jan 2006
Administrative works and committees
Administrative work and committee Date
Graduation Committee, Faculty of 2013/2014 and 2014/2015
Medicine, University of Jordan
Representative of Anatomy department 2013/2014 and 2014/2015
at faculty board, Faculty of Medicine,
University of Jordan
Student Counseling Committee, Faculty 2015/2016
of Medicine, University of Jordan
Student Research Forum (SRF) Judging, 2015/2016
Faculty of Medicine, University of
Jordan
Curriculum Committee, Faculty of 2015/2016
Medicine, University of Jordan
Educational Credential Assessment, 2015/2016
Faculty of Medicine, University of
Jordan
Accreditation and quality assurance center Curriculum Vitae The University of Jordan
3
Recent Publications within last five years
Name of researcher Research title, Publisher, Date
(2017) Incidence and anatomical
variations of accessory navicular bone
in patients with foot pain: A
retrospective radiographic analysis.
Clin Anat.
Kalbouneh H, Alajoulin O, Alsalem M,
Humoud N, Shawaqfeh J, Alkhoujah M,
Abu-Hassan H, Mahafza W, Badran D
(2017) Age Prediction in the Adult
based on the Pulp-to-Tooth Ratio in
lower third molars: A Cone-beam CT
study. International Journal of
Morphology 35.
Alsoleihat F, Alshayyab M, Kalbouneh
H, Al-Zer H, Ryalat S, Abeer Alhadidi,
Saoud H, Shaweesh A, Al-Omoush S,
Khraisat A
(2016) Forebrain-specific loss of synaptic
GABA receptors results in altered
neuronal excitability and synaptic
plasticity in mice. Mol Cell Neurosci.
72:101-113.
O'Sullivan G.A., Jedlicka P., Chen H.X.,
Kalbouneh H., Ippolito A., Deller T.,
Nawrotzki R.A., Kuhse J., Kalaidzidis Y.L.,
Kirsch J., Schwarzacher S.W., Betz H.
(2016) The patellofemoral joint alignment
in patients with symptomatic accessory
navicular bone. Italian Journal of Anatomy
and Embryology. 121(2): 148-158
Heba M Kalbouneh, Abdullah O
Alkhawaldah, Omar A Alajoulin, Mohammad
I Alsalem
(2016) Role of PPARα and PPARγ in
Mediating the Analgesic Properties of
Ibuprofen in vivo and the Effects of Dual
PPARα/γ Activation in Inflammatory Pain
Model in the Rat. International Journal of
Pharmacology. 12:812-820
Mohammad Alsalem, Ahmad Altarifi, Heba
Kalbouneh, Heba Al- Zer, Belal Azab,
Khalid El- Salem
(2016) Normal values of Quadriceps
angle and its correlation with
anthropometric measures in a group of
Jordanians. JRMS 23:53-58.
Islam Tarawneh, AL-Ajoulin O, Abdullah
Alkhawaldah, Heba Kalbouneh, Amjad
Shatarat, Darwish Badran, Maher Hadidi
(2015) Dental pulp stem cells-derived
schwann cells for peripheral nerve injury
regeneration. Neural Regeneration
Research. 10:1945-1946
Al-Zer H., Kalbouneh H.
(2015) Spontaneous Achilles tendon
rupture in alkaptonuria. Saudi Med J.
36:1486-1489
Alajoulin O.A., Alsbou M.S., Ja'afreh S.O.,
Kalbouneh H.M.
(2015) Ultrasonographic assessment of
splenic volume and its correlation with
body parameters in a Jordanian
population. Saudi Med J. 36:967-972
Badran D.H., Kalbouneh H.M., Al-Hadidi
M.T., Shatarat A.T., Tarawneh E.S., Hadidy
A.M., Mahafza W.S.
Accreditation and quality assurance center Curriculum Vitae The University of Jordan
4
(2014) Cyclin-dependent kinase 5 is
involved in the phosphorylation of
gephyrin and clustering of GABAA
receptors at inhibitory synapses of
hippocampal neurons. PLoS One.
9:e104256.
Kalbouneh H., Schlicksupp A., Kirsch J.,
Kuhse J.
(2012) Phosphorylation of gephyrin in
hippocampal neurons by cyclin-dependent
kinase CDK5 at Ser-270 is dependent on
collybistin. J Biol Chem. 287:30952-
30966.
Kuhse J., Kalbouneh H., Schlicksupp A.,
Mukusch S., Nawrotzki R., Kirsch J.
Scientific conferences and symposia
Place and date of اType of participation
conference
Conference Title
Bahjat Al-Talhouni Participant
Auditorium- University
of Jordan. 2016
Arab Simulation Conference in
Medical Education
8th World Congress on Healthcare Dubai 2016 Speaker
and Medical Tourism (Health
Congress 2016)
Accreditation and quality assurance center Curriculum Vitae The University of Jordan
5
Training courses
Date
Name of course
Taylor & Francis Research Seminar- How 28th March 2017
To Get Author Published,
University of Jordan
Scientific research and academies: 18th March 2017
importance, sources of funding and methods
of documentation.
Association of Jordanian Women Academics
Web of science and Endnote training 26th Oct. 2016
Workshop. The intellectual Property and
Science department of Thomson Reuters,
University of Jordan
How to integrate basic clinical skills and 6th Oct. 2016
simulation adjuncts in an undergraduate
medical curriculum, University of Jordan
Briefing and debriefing practices in 5th Oct.2016
simulation, University of Jordan
2nd April, 2016
Academic and Educational
Counseling Workshops, School of
Medicine, University of Jordan
Presenting Research Results, 14th -15th May 2012
Department of Key Competencies and
Graduate Academy of the University of
Heidelberg, Germany.
16th -27th January2012
Laboratory Animal Science and
Methods of Animal Experimentation,
Faculty of Biomedical Sciences,
Ruprecht-Karls-University Heidelberg,
Germany
5th -13th June 2009
Development of Educational Skills,
University of Jordan
Accreditation and quality assurance center Curriculum Vitae The University of Jordan
6
Teaching activities
Taught Courses Bachelor Graduate
Introduction to histology for medicine
Histology 1 for dentistry
Anatomy of limbs, abdomen and thorax
for dentistry
General anatomy for nursing
Anatomy 2 for rehabilitation
Membership in scientific and professional bodies and societies
Date
Name and place of scientific body and society
Jordan Dental Association 2006
Association of Jordanian Women Academics 2015
Alkaptonuria Research Association 2015
Three circles of ALEMAT 2014
German Graduate Association 2013
Достижения и награды
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